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I-Varicella I-Vaccine ye-Chicken Pox i-Live Atttenated

Ulwazi oluSiseko

Umzekelo No.: 0.5ml/vial

Ingcaciso yeMveliso

Uvavanyo

Inkqubo ye-Electroporation yovavanyo lwe "DNA vaccine"

Inani lezitofu ezinokutsha nazo ziphuhliswa kwaye zisetyenziswa:

  • Izigulana ze-Dendritic zegesi zidibanisa iiseli ze-dendritic kunye nama-antigens ukwenzela ukubonisa ama-antigen kumaseli egazi amhlophe omzimba, ngaloo ndlela ivuselela ukuphendula kwamagciwane. Ezi zitofu zibonise ezinye iziphumo eziphambili zokuphatha izicubu zeengqondo [27] kwaye ziyavavanywa kwi-melanoma enobungozi. [28]
  • I- Vector Vector - ngokudibanisa i-physiology yomzimba omnye kunye ne- DNA yesinye, ukukhuselwa kungakhutshwa ngokubhekiselele kwizifo ezinesifo esincinci
  • Ukugonywa kwe-DNA - enye indlela, indlela yokuhlola yokugonya ebizwa ngokuba yi- DNA yokugonywa , eyenziwe kwi-DNA ye-Agent, ephantsi kokuphuhliswa. Indlela ephakanyisiweyo yindlela yokufakelwa (kunye nesibonakaliso , ukuphuculwa ngokusetyenziswa kwe- electroporation , okubangela ukuba i-immune system recognition) ye-DNA okanye i-DNA ye-bacteria kumaseli omntu okanye asezilwaneni. Amanye amaseli omzimba wokuzivikela omzimba aqonda ukuba iiprotheni ezivakalisiweyo ziya kuhlasela ukuhlaselwa kwezi proteins kunye neeseli ezizithethayo. Ngenxa yokuba iiseli zihlala ixesha elide kakhulu, ukuba i- pathogen ebonisa ngokuqhelekileyo ezi proteins idibana nakwixesha elizayo, ziya kuhlaselwa ngokukhawuleza nge-immune system. Enye inzuzo yokufumana iigciwane ze-DNA kukuba kulula kakhulu ukuvelisa nokugcina. Ngomhla ka-2015, ukugonywa kwe-DNA kusesilingo kwaye akuvunyelwanga ukusetyenziswa kwabantu.
  • Iigciwane ze-T-cell receptor peptide ziphantsi kophuhliso lwezifo ezininzi zisebenzisa imizekelo ye- Valley Fever , stomatitis , kunye ne- dopatitis ye-atopic . Ezi peptide ziboniswe ukuba zilungise ukuveliswa kwe- cytokine kwaye ziphucule ukukhulelwa komzimba.
  • Ukujoliswa kweeprotheriya ezichongiweyo ezibandakanyekayo ekuzaliseni ukuvinjelwa kwemithi kuya kunciphisa indlela yokusetyenziswa kwe-bacterial virulence. [29]

Ngelixa ezininzi izitofu zenziwa ngokusebenzisa izixhobo ezingenakwenziwa okanye ezicwangcisiweyo ezivela kwizinto ezincinci, izitofu zokugonywa zihlanganiswe ngokubanzi okanye zonke iipeptide zokwenziwa, i-carbohydrates, okanye i-antigens.

Varicella Vaccine

Iikhathalo zomkhiqizo : I-Varicella Vaccine (Live) > Iimveliso ezigqityiweyo

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